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  2014 - 2015 Grants 

London Health Sciences

Pamela Greenaway Kohlmeier Translational Breast Cancer Research Unit (TBCRU)

The Breast Cancer Society of Canada has a very long and strong relationship with the TBCRU. The work of the unit is managed by Dr. Ann Chambers with assistance from Dr. Alison Allan. The Society funds are used to support the ongoing work of the TBCRU and are divided between Senior Scientists stipend, small grants program, studentships and a very small allotment for equipment needs. Dr. Chambers manages applications for breast cancer research funding from the London area, regardless of institutional affiliations. As the TBCRU is located a few floors above the London Regional Cancer Program facility there is optimal opportunity for collaboration between research scientists and treatment physicians; an excellent example of a “bench to bedside”  philosophy.  Watch the TBCRU video!

Ongoing research projects include:

- Respiratory Motion Management for Patients Receiving Radiotherapy for Left-Sided Breast Cancer ~ Omar El-Sherif. To read more visit his  Pink Link Researcher's Blog (with video)

- The Potential Role of Pathogenic and Commensal Bacteria in Promoting and Controlling Breast Cancer ~ Camilla Urbaniak. To read more visit her  Pink Link Researcher's Blog

- The Role of Insoluble ECM Factors in Lung-Specific Metastatic Behavior of Breast Cancer Cells ~ Ying Xia, PhD. To read more visit her Pink Link Researcher's Blog 

Sunnybrook Hospital - Toronto

The Society's funding to Sunnybrook does not involve a research team approach. Funds are used to support the work of Dr. Greg Czarnota and his project using ultrasound microbubbles to enhance the effectiveness of radiation treatments on breast cancer patients. It is anticipated that this new procedure will soon be tested in clinical trials with patients at the Odette Cancer Centre.  

Ongoing projects include:

- Dr. Czarnota's exciting new research involves the use of microbubbles and ultrasound to effectively target tumours and enhance treatment in breast cancer patients. Watch Dr. Czarnota's video to find out more.

Alberta Health Services - Calgary 

Managed by Dr. Alexander Paterson out of the Tom Baker Cancer Treatment Centre, this program focusses on seed funding (small grants). Dr. Paterson has formed a committee to vet applications from the Calgary area. The committee also provides annual updates to BCSC with details about currently funded projects.  

Ongoing projects include: 

- Opportunity for Breast Cancer Prevention Amongst Women in Southern Alberta: Frequency of Incident High Risk Cases Over the Past 5 Years ~ B Walley, ML Quan, R Perrier, P Bridge, Kim Plaikie

- Outcomes & Patterns of Care Following Sentinel Lymph Node Biopsy for Early Stage Breast Cancer: Clarifying the Role for Axillary Node Dissection ~ Barbara Walley, Sasha Lupichuk, Tony Magliocco

- Tamoxifen Active Metabolites & CYP2D6 Genotype Studies ~ ESM Ng, B Kangarloo, M Konno, A Paterson, AM Magliocco

QEII Foundation - Halifax

Managed by Dr. Michael Johnston of the Beatrice Hunter Cancer Research Institute and in partnership with the QEII Health Sciences Centre, this program operates similarly to the one in London. The Breast Cancer Society's funds are used to support a breast cancer research award program and a cancer research training program. 

The following is just one example of the type of research being conducted. Dr. David Hoskin and his team are investigating an alternative to chemotherapeutic drugs which kill rapidly dividing cells, both cancerous and healthy in the immune system.  Certain substances found in herbs used in traditional Chinese medicine are able to kill both drug-sensitive and drug-resistant cancer cells without harming healthy cells and without undesirable side-effects. Their research has shown that the antimalarial compound artesunate found in Chinese wormwood causes breast cancer cells to die by a process of apoptosis. This research will determine the mechanism by which artesunate causes apoptosis in breast cancer cells and establish the effectiveness of artesunate alone or in a combination with conventional chemotherapeutic drugs in mouse models of breast cancer. These studies will provide a sound rationale for the possible clinical application of artesuante in the treatment of advanced breast cancer. QEll research. 

Ongoing projects include:

-Targeted Delivery of Pleurocidin-Family Peptide NRC-03 to Breast Carcinoma Cells ~ Dr David Hoskin, Dr. Laurence Madera 

-Retinoid-Based Treatment Profiling Strategies for Triple-Negative Breast Cancers Based on Gene Expression and Intrinsic Subtypes ~ Dr Paola Marcato, Dr Carman Giacomantonio 

-Pre-Clinical Evaluation of Novel Small Molecules that Target Breast Cancer Cell Metabolism ~ Dr. Paola Marignani

Canadian Institute for Health Research (CIHR)

The Canadian Institutes of Health Research (CIHR) is Canada’s federal funding agency for health research. By partnering with CIHR we are able to offer the Eileen Iwanicki Award for Post-Doctoral Fellowships in Breast Cancer Research. Every dollar we grant to CIHR is matched by federal dollars, doubling the impact of our donors. The Breast Cancer Society's has a matching partnership with CIHR for the Eileen Iwanicki Post-Doctoral Fellowship for Breast Cancer Research. This fund was created as recognition for a bequest from Eileen Iwanicki of Fredericton, NB. CIHR manages the applications and the peer review process. The Society recently signed a new agreement to extend the program for another five years.

Cancer Care Manitoba

This new initiative with Cancer Care Manitoba will support three studentships for one year term. These students will work with the Manitoba Breast Cancer Research Team located in Winnipeg. 

 


 


 
 
The Breast Cancer Society of Canada is a tax-exempt and registered charity (charitable registration number 137969861R0001).